Not medical advice. This content is for informational purposes only, backed by cited research. Consult a healthcare provider for personal guidance.
Up to 40% of pregnant women experience constipation. We researched which laxatives OB-GYNs recommend during pregnancy and which to avoid completely.
OUR #1 PICK

Fiber is the only intervention with actual trial evidence in pregnancy — the Cochrane review found it improved constipation versus no treatment, and found no data at all for stool softeners or osmotics. It also addresses a real cause, since fiber intake often collapses when nausea narrows your diet.
If you're pregnant and constipated, first: you're in very good company. Up to 40% of pregnant women deal with constipation at some point, thanks to the delightful combination of progesterone slowing your digestive system, prenatal iron supplements backing things up further, and a growing baby pressing on your intestines. The good news is there are safe, effective options — but "safe during pregnancy" narrows the field significantly, and that's exactly what we sorted through for you.
The single most important rule for pregnancy constipation: avoid stimulant laxatives (Dulcolax, Senokot, Ex-Lax, castor oil) unless your OB specifically tells you otherwise. These products force intestinal muscle contractions, and while the risk to pregnancy is theoretical rather than proven, OB-GYNs universally recommend avoiding them when safer alternatives exist.
Understanding why this is happening helps explain why certain products are recommended:
Progesterone relaxes smooth muscle — including the muscles of your intestines. Your entire digestive tract slows down, meaning stool sits longer and loses more water, becoming harder and more difficult to pass.
Prenatal iron supplements are a major contributor. Iron is constipating even outside of pregnancy. Combined with the progesterone slowdown, iron supplements can turn mild constipation into a significant daily problem.
Physical compression — especially in the second and third trimesters — means the growing uterus physically presses on your intestines, further slowing transit.
Reduced physical activity in later pregnancy contributes as well. Movement stimulates gut motility, and reduced activity means reduced motility.
Dietary changes due to morning sickness, food aversions, and fatigue often reduce fiber and fluid intake — both of which are critical for regularity.
For this guide, we heavily adjusted our standard weights to prioritize safety:
Pregnancy Safety — 40% (the defining criterion — nothing else matters if it's not safe) Effectiveness — 25% (does it actually work for pregnancy-specific constipation?) Tolerability — 20% (will it worsen nausea, bloating, or other pregnancy symptoms?) Ease of Use — 10% (compliance during a time when you have 100 other things to manage) Value — 5%
We consulted OB-GYN guidelines, FDA pregnancy categories, and the American College of Obstetricians and Gynecologists (ACOG) recommendations in making these selections.
Most OBs recommend a layered approach:
Start with diet and water. Aim for 25-30 grams of fiber daily (prunes, pears, beans, whole grains) and at least 8-10 glasses of water. This resolves mild constipation for many women without any medication.
Add Colace if diet alone isn't enough. One capsule twice daily is the standard starting regimen. Give it 3-5 days to take effect.
Add Metamucil (or switch to capsule form) if you need more fiber but food aversions make it hard to eat high-fiber foods. Start with half a dose to minimize gas.
Escalate to MiraLAX with your OB's approval if Colace plus fiber isn't cutting it. Many OBs add MiraLAX for patients in the second and third trimesters who aren't getting relief from softer interventions. The gentlest option versus the best-evidenced one covers that step-up decision, docusate against psyllium covers the softener-plus-fiber pairing most OBs start with, and our MiraLAX pregnancy notes and docusate safety review go deeper on each.
Talk to your OB if none of the above is working after 1-2 weeks. Prescription options exist for severe pregnancy constipation, and hemorrhoid prevention becomes more important as the pregnancy progresses.
If your prenatal vitamin contains iron and constipation is severe, ask your OB about slow-release iron formulations or taking iron every other day instead of daily. Research shows that every-other-day iron dosing can actually improve absorption while significantly reducing constipation. This one change resolves constipation for some pregnant women entirely, without needing any laxative at all.
Your OB can also check your iron levels — you may not need supplemental iron if your levels are already adequate, in which case switching to an iron-free prenatal eliminates the biggest constipation contributor.


Our Pick
Our Pick
“The orange flavor is strong and the psyllium gives it a thick, slightly gritty texture that takes getting used to. Must drink immediately after mixing — it gels fast and becomes undrinkable.”
Fiber is the only intervention with actual trial evidence in pregnancy. The Cochrane review of constipation in pregnancy found that fiber supplementation improved constipation compared with no intervention — and it found no data at all for stool softeners or osmotic laxatives. Psyllium also addresses a real root cause: fiber intake often collapses in pregnancy when nausea narrows what you can face eating. The gritty texture is a genuine problem if you're already queasy, so use the capsules if the powder is intolerable.
Typically $15–$40
Our estimate of typical retail cost — not a live Amazon price. Check Amazon for the current price.


Runner Up
Runner Up
“Unflavored powder dissolves completely in any liquid — truly tasteless, which is its biggest advantage over flavored competitors.”
PEG 3350 has the strongest evidence of any laxative for constipation generally, and it is minimally absorbed into the bloodstream, which is why most OBs are comfortable with it. Be aware of what we do and don't know: there is no pregnancy trial data for osmotic laxatives — the Cochrane review says so explicitly. Its use in pregnancy rests on the absence of a safety signal and on how little of it gets absorbed, not on a trial showing it works in pregnant women. Confirm with your own doctor.
Typically $10–$30
Our estimate of typical retail cost — not a live Amazon price. Check Amazon for the current price.


Widely Used, Weak Evidence
Widely Used, Weak Evidence
“Standard-sized soft gel capsules with a slightly oily feel. The liquid form has a bitter medicinal taste that most people find unpleasant — stick with capsules if you can.”
Colace is the product OB-GYNs most commonly suggest, and we are not going to pretend otherwise — but we have to be straight about the evidence, because it is poor. A randomized, double-blind, placebo-controlled trial found docusate gave no benefit over placebo. The Cochrane review of constipation in pregnancy found no data on stool softeners at all, and the AGA-ACG guideline does not evaluate docusate. What it has going for it is that it is exceptionally gentle and very widely used. What it does not have is evidence that it works. If it helps you, there is no reason to stop; if it isn't helping, that is entirely consistent with the evidence, and you should try something else rather than assume you're doing it wrong.
Typically $6–$18
Our estimate of typical retail cost — not a live Amazon price. Check Amazon for the current price.
| Product | Type | Active Ingredient | Onset | Price | Rating | Best For |
|---|---|---|---|---|---|---|
| Metamucil | fiber | Psyllium Husk | 12-72 hours (daily use for best results) | Typically $15–$40 | Daily constipation prevention | |
| MiraLAX | osmotic | Polyethylene Glycol 3350 (PEG 3350) | 1-3 days | Typically $10–$30 | Daily use | |
| Colace | stool-softener | Docusate Sodium | 1-3 days | Typically $6–$18 | Pregnancy (OB-recommended) |
OTC products work well for most people, but see a doctor if you experience any of the following:
A GI doctor can evaluate your symptoms and prescribe treatments not available over the counter. Ask your primary care doctor for a referral, or search for a board-certified gastroenterologist through the American Gastroenterological Association. Many GI practices now offer telehealth consultations.
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Medical Disclaimer
This content is for informational purposes only and does not constitute medical advice. Always consult a healthcare professional before starting any new medication or supplement, especially if you are pregnant, nursing, taking prescription medications, or have a pre-existing medical condition. Product recommendations are based on publicly available clinical research and are not a substitute for professional medical guidance. Read our full disclaimer.
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